Thursday, February 25, 2010

Protein as Enzyme 1NPF

The protein that I found is 1NPF myoglobin in the horse heart. My protein clearly has a primary structure because it has an amino acid sequence. My protein has other multiple structures too. All protiens have secondary structure, 1NPF has 6 alpha sheets. It has tertiary structure because it has 3D shape and folds and it twists. It has no quaternary structure because my protein is lacking multiple subunits.
My protein was isolated from equus caballus. This protein is a myoglobin protein used to store oxygen. This protein would be useful in research because its function is already known. Also it plays an important role by storing oxygen so if the scientists needed to research how proteins can store oxygen this is one they could use. In this particular study 1NPF was used to help look at another proteins function. “To the best of our knowledge, the crystal structure of hh Mb(EtNO) is the first such determination of a nitrosoalkane adduct of a heme protein (Copeland DM).” This protein can be useful in finding the function of this other protein so in a research setting one could use this protein with a known function to find out the function of another protein.


Works Cited:
Reference:
Copeland DM, West AH, Richter-Addo GBCrystal structures of ferrous horse heart myoglobin complexed with nitric oxide and nitrosoethaneProteins v53, p.182-192
http://www.ncbi.nlm.nih.gov/Structure/mmdb/mmdbsrv.cgi?Dopt=s&uid=25253&log$=seqview_protein_structuread_title

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